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It leaves a minimal footprint on system resources, so the overall performance of the computer is not hampered. To sum things up, online-stopwatch offers an intuitive layout and a handy set of parameters for helping you time your activities quickly and with minimum effort. Antigen-induced increases in E-selectin and intercellular adhesion molecule-1 expression in nasal mucosa are attenuated by pre-treatment with oral antihistamines. Recent studies indicate that selectins and intercellular adhesion molecule-1 (ICAM-1) play a key role in facilitating the diapedesis of eosinophils from the nasal mucosa to the airway lumen in response to antigen challenge. The aim of this study was to establish whether pre-treatment with antihistamines inhibits antigen-induced changes in E-selectin and ICAM-1 expression in nasal mucosa. 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